Description
AV-DERMACORE: GHK-Cu + Hyaluronic Acid Research Cream
AV-DERMACORE is an Aevigenix branded research formulation containing GHK-Cu (copper peptide) and hyaluronic acid (HA), supplied as a finished cream in a sealed 60 mL cosmetic jar.
The formulation is listed as containing 1% GHK-Cu and 1% hyaluronic acid in an emollient cream base. AV-DERMACORE is designated for nonclinical laboratory research involving analytical characterization, formulation composition, physicochemical properties, and material stability.
Understanding GHK-Cu
GHK-Cu is a copper-binding peptide complex formed through the interaction of copper(II) with glycyl-L-histidyl-L-lysine (GHK), a naturally occurring tripeptide consisting of glycine, histidine, and lysine.
The peptide’s amino acid structure provides coordination sites for copper ions. This molecular relationship is relevant to nonclinical investigations of peptide-metal interactions and their physicochemical characteristics.
- Peptide Name: Glycyl-L-histidyl-L-lysine (GHK).
- Amino Acid Sequence: Gly-His-Lys.
- Peptide Length: Three amino acid residues.
- Classification: Copper(II)-peptide coordination complex.
Hyaluronic Acid and Formulation Science
Hyaluronic acid is a glycosaminoglycan composed of repeating disaccharide units. Its water-binding and viscosity-related characteristics make it relevant to laboratory investigations of formulation structure and material behavior.
AV-DERMACORE lists hyaluronic acid at 1% of the finished formulation. Its molecular weight distribution, chemical form, and precise concentration basis should be confirmed through applicable supplier documentation.
Research Cream Composition
AV-DERMACORE combines the listed research components in an emollient cream base. The formulation contains water, oils, emulsifying agents, consistency modifiers, and other ingredients that contribute to its physical characteristics.
Named Components: 1% GHK-Cu copper peptide and 1% hyaluronic acid.
Full Ingredient List: Distilled Water, Ceteareth-20, Glycerin, Sunflower Oil, Shea Butter, Coconut Oil, Glyceryl Stearate, GHK-Cu, Hyaluronic Acid, Beeswax, Dimethicone, Phenoxyethanol, Palm Oil, Sodium Polyacrylate, Tocopherol (Vitamin E).
The complete formulation should be verified against the finished product’s manufacturing specifications. Ingredient concentrations other than the two named 1% components have not been provided.
Laboratory Evaluation of Cream Formulations
Nonclinical laboratory characterization of a cream formulation may include evaluation of its composition, physical properties, and changes under defined experimental conditions.
- Composition: Identification and quantification of the named formulation components.
- Physical Characteristics: Appearance, consistency, and viscosity.
- Physicochemical Properties: pH and relevant material characteristics.
- Stability: Evaluation of physical and chemical changes under controlled laboratory conditions.
- Batch Consistency: Comparison of analytical characteristics between production lots.
Quality, Purity and Analytical Testing
Supplier-provided information reports a purity result of at least 99.1%, with high-performance liquid chromatography (HPLC) and mass spectrometry identified as the analytical methods.
HPLC may be used to evaluate chromatographic purity, while mass spectrometry supports molecular identity analysis. The relevance of these findings depends on which material was tested and the methods used.
The reported purity must be matched to the applicable Certificate of Analysis. Testing of GHK-Cu raw material does not independently establish the purity, stability, or complete composition of the finished AV-DERMACORE cream.
Lot Number: 3009Q
Batch Reference: AV-9964
Reported Purity: ≥99.1%, pending confirmation against the applicable analytical report.
Packaging, Storage and Laboratory Handling
AV-DERMACORE is supplied as a finished cream in a sealed cosmetic jar. It is not a lyophilized peptide powder and does not require reconstitution.
The supplier has referenced refrigerated or frozen storage conditions. However, storage recommendations for a finished cream must account for the complete formulation, including its emollient base and other ingredients.
Refrigeration or freezing should only be recommended when supported by finished-formulation stability documentation. Researchers should follow verified product-specific storage instructions.
Frequently Asked Questions
AV-DERMACORE is a research cream containing GHK-Cu copper peptide and hyaluronic acid, supplied in a sealed 60 mL container.
The supplier lists 1% GHK-Cu and 1% hyaluronic acid in the finished formulation. The concentration basis should be confirmed through manufacturing documentation.
No. The product is supplied as a finished cream and does not require reconstitution.
The supplied information does not establish whether the reported purity applies to the GHK-Cu raw material or the finished cream. The applicable Certificate of Analysis should be reviewed to determine the scope of testing.
AV-DERMACORE is designated exclusively for nonclinical laboratory research. Not intended for human consumption, topical application to people or animals, clinical use, or veterinary administration. Product identity, composition, and stability should be confirmed through appropriate documentation.

